Title:
【発明の名称】11-アリール-5,6-ジヒドロ-11H-ジベンズ[b,e]アゼピン類の合成
Document Type and Number:
Japanese Patent JP2001524469
Kind Code:
A
Abstract:
Disclosed is a three step synthesis of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines from a 2-aminobenzophenone represented by the following structural formula:and a starting material represented by the following structural formula:Phenyl Ring A, Phenyl Ring B and Phenyl Ring C are independently unsubstituted or substituted with one, two or three substituents. Each substituent on Phenyl Ring A, Phenyl Ring B and Phenyl Ring C is independently chosen.R is -H, a aliphatic group, a substituted aliphatic group, an aryl group, a substituted aryl group, -C(O)-R', -C(O)-H, -C(O)-NHR', -S(O)2R', -C(O)-C(O)-R', -C(O)-C(O)-H, -C(S)-R', -C(S)-H, -C(O)-OR', -C(S)-OR', -C(O)-SR', -C(S)-SR', -C(O)-NR'2 or -C(O)-C(S)-R'. R' is an aliphatic group, a substituted aliphatic group, an aryl group or a substituted aryl group.R1 is a leaving group.The present invention also includes novel compounds which are intermediates in the preparation of 11-aryl-5,6-dihydro-11H-dibenz[b,e]azepines.
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Inventors:
Mauza, Adele, M.
Lombardy, Richard, Jay.
Haider, Reem, M.
Sun, Min Nua
Lombardy, Richard, Jay.
Haider, Reem, M.
Sun, Min Nua
Application Number:
JP2000522086A
Publication Date:
December 04, 2001
Filing Date:
November 12, 1998
Export Citation:
Assignee:
Farm-Eco Laboratories, Inc.
International Classes:
C07C213/00; C07C215/68; C07C221/00; C07C225/22; C07D223/20; (IPC1-7): C07D223/20; C07C213/00; C07C215/68; C07C221/00; C07C225/22
Attorney, Agent or Firm:
Yoshinori Hosoda
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