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Title:
【発明の名称】モルフィン-6-グルクロニドの合成
Document Type and Number:
Japanese Patent JP2002517504
Kind Code:
A
Abstract:
The invention provides a novel method for synthesizing Morphine-6-Glucuronide comprising the step of reacting 3-O-pivaloyloxymorphine and methyl 1alpha,2-ethylorthopivalate-3,4-di-O-pivaloylglucouronate.

Inventors:
Parsons, Philip James
Ewin, Richard Andrew
Application Number:
JP2000553438A
Publication Date:
June 18, 2002
Filing Date:
June 04, 1999
Export Citation:
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Assignee:
Senes Limited
International Classes:
C07D213/06; C07D213/127; C07D213/16; C07D489/02; C07H9/04; C07H13/04; C07H13/06; C07H17/00; (IPC1-7): C07D489/02; C07D213/16; C07H13/06; C07H17/00
Domestic Patent References:
JPH09505999A1997-06-17
JPH07501317A1995-02-09
JPH09505999A1997-06-17
JPH07501317A1995-02-09
Foreign References:
WO1996028450A11996-09-19
WO1996028450A11996-09-19
Other References:
JPN6010002881, Tetrahedron Lett., 1995, 36, 3949−3950
JPN6010002883, Liebigs Ann. Chem., 1983, 570−574
JPN6010002886, Carbohyd. Res., 1971, 16, 17−27
JPN6010002887, Tetrahedron Lett., 1990, 31, 6167−6170
JPN6010002889, J. Pharm. Sci., 1996, 85, 690−694
Attorney, Agent or Firm:
Takashi Ishida (4 others)