【発明の名称】光学活性アミノインダノールの合成

Title:

【発明の名称】光学活性アミノインダノールの合成

Document Type and Number:

Japanese Patent JPH11504929

Kind Code:

A

Abstract:

PCT No. PCT/EP96/01884 Sec. 371 Date Oct. 28, 1997 Sec. 102(e) Date Oct. 28, 1997 PCT Filed May 7, 1996 PCT Pub. No. WO96/35660 PCT Pub. Date Nov. 14, 1996A process for preparing enantiomerically pure cis-1-amino-2-hydroxyindane, which comprises a) converting racemic trans-1-aminoindan-2-ol with acids or acid derivatives of the general formula RCOX by conventional methods into amides of type A A b) adding seed crystals of one enantiomer to a super-saturated solution or melt of the racemic amide A, c) isolating the crystals which have separated out, and again supersaturating the remaining mother liquor or melt after dissolving racemic amide A, and adding seed crystals of the other enantiomer, leading to selective crystallization of the latter, d) converting the resulting enantiomerically pure trans amide by conventional methods into the enantiomerically pure cis-1-amino-2-hydroxyindane.

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Inventors:

Christoph Nupling
Wolfgang Ladner

Application Number:

JP53373296A

Publication Date:

May 11, 1999

Filing Date:

May 07, 1996

Export Citation:

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Assignee:

BASF Akchen Gezel Shaft

International Classes:

C07C213/02; C07C213/08; C07C213/10; C07C217/52; C07C233/23; C07C271/24; C07C271/56; (IPC1-7): C07C217/52; C07C213/02; C07C233/23; C07C271/24; C07C271/56

Attorney, Agent or Firm:

Toshio Yano (3 outside)

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