Title:
【発明の名称】移植可能なものとしての合成タンパク質
Document Type and Number:
Japanese Patent JP3378254
Kind Code:
B2
Abstract:
Methods and compositions are provided which are useful for delivering a biologically active substance to a localized site in vivo and for altering the physical dimensions of a body tissue. These methods and compositions employ protein polymers having varying ratios of elastin-like, collagen-like, keratin-like repeating units and repeating units which promote protein crystallization such as silk-like repeating units. By varying the length of segments of the repeating units and/or the concentration of the protein polymers in the composition, the rate of delivery of a biologically active substance to a localized site can be greatly varied. Moreover, because the compositions are capable of acquiring a non-liquid form under normal physiological conditions, they find use as biocompatible tissue augmentation products.
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Inventors:
Capello, joseph
Application Number:
JP52357195A
Publication Date:
February 17, 2003
Filing Date:
March 10, 1995
Export Citation:
Assignee:
Protein Polymer Technologies, Inc.
International Classes:
C12N15/09; A61L17/00; A61L17/10; A61L27/00; A61L27/22; A61L31/00; A61L31/04; C07K14/00; C07K14/78; C07K17/00; C08J5/18; C08L89/00; C12N1/21; C12N15/11; C12P21/02; D01F4/00; A61K38/00; (IPC1-7): C07K14/00; A61L17/00; A61L27/00; A61L31/00; C12N15/09
Domestic Patent References:
| JP3502935A |
Other References:
Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｐｒｏｇｒｅｓｓ，（１９９０）Ｖｏｌ．６，Ｎｏ．３，ｐ．１９８−２０２
Attorney, Agent or Firm:
Takashi Ishida (2 outside)