Title:
【発明の名称】タキソール誘導体
Document Type and Number:
Japanese Patent JPH09500138
Kind Code:
A
Abstract:
A compound or prodrug thereof having the formula ain of taxol and Z is selected from the group consisting of -CHO, -CH2OH, -CH2OR', -CH2NR'R'', -CH=NR', -CH=NOR', -CH=NNR=R'', -CH(OH)SO3Na, -CH2OPO3=, -CH2OSO3=, -CN and a radical of the formula where X and Y are independently selected from -O-, -S-, and -N(R')-, as well as a method for preparing the compounds of the invention, a method of their use for the inhibition of tumors and pharmaceutical compositions containing the same.
Inventors:
Klein, Larry El
Marling, Clarence The Ray
Marling, Clarence The Ray
Application Number:
JP50474694A
Publication Date:
January 07, 1997
Filing Date:
July 15, 1994
Export Citation:
Assignee:
Abbot Laboratories
International Classes:
A61K31/335; A61K31/337; A61P35/00; C07D305/14; (IPC1-7): C07D305/14; A61K31/335
Other References:
BOT.BULL.ACADEMIA SINICA=1991
PLANT PHYSIOLOGY=1989
PLANT PHYSIOLOGY=1989
Attorney, Agent or Firm:
Yoshio Kawaguchi (2 outside)