Title:
【発明の名称】治療剤
Document Type and Number:
Japanese Patent JP2003503343
Kind Code:
A
Abstract:
A method of treating obesity and related conditions comprising the administration of a therapeutically effective amount of a compound of formula (I) including pharmaceutically acceptable salts, solvates, racemates, enantiomers, diastereoisomers and mixtures thereof in which: R1 represents H or one of the following groups (optionally substituted with one or more of halo, cyano, hydroxy or amino): C1-6alkyl, C1-6alkoxy or C1-6alkanoyl; R2 and R3 independently represent H or one of the following groups (optionally substituted with one or more of halo, cyano, hydroxy or amino): C1-6alkyl, C1-6alkoxy, C1-6alkanoyl, C1-6alkylthio, C1-6alkylsulphinyl, C1-6alkylsulphonyl or hydroxy; R4 and R5 independently represent H, C1-6alkyl or R4 and R5 combined together with the carbon atom to which they are attached represent C3-6cycloalkylidene (each alkyl or cycloalkylidene being optionally substituted with one or more of halo, cyano, hydroxy, amino or C1-6alkyl); and R6, R7 and R8 independently represent H, halo, hydroxy, mercapto, nitro, cyano or one of the following groups (optionally substituted with one or more of halo, cyano, hydroxy or amino; and any nitrogen atom being optionally substituted with one or more C1-6alkyl): C1-6alkyl, C1-6alkanoyl, C1-6alkoxy, C2-6alkoxycarbonyl, carboxy, C1-6alkanoyloxy, C1-6alkylthio, C1-6alkylsulphinyl, C1-6alkylsulphonyl, C1-6alkylsulphonylamino, sulphamoyl, carbamoyl, C2-6alkylcarbamoyl or C1-6alkanoylamino; to a mammal in need thereof.
Inventors:
Kilpatrick, Ian Chyars
Application Number:
JP2001505896A
Publication Date:
January 28, 2003
Filing Date:
June 16, 2000
Export Citation:
Assignee:
Knorr GMBH
International Classes:
C07D487/04; A61K31/519; A61P3/00; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P25/00; A61P25/20; A61P25/34; (IPC1-7): A61K31/519; A61P3/04; A61P3/06; A61P3/10; A61P25/00; C07D487/04
Attorney, Agent or Firm:
Yoshio Kawaguchi (5 outside)