Title:
【発明の名称】チオールスルホンアミド メタロプロテアーゼインヒビター
Document Type and Number:
Japanese Patent JP2000515153
Kind Code:
A
Abstract:
This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfonamide inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with phatological matrix metalloproteinase activity related to MMP-13.
Inventors:
Docre Senzo, Gary
Abbas, Zaheel, Es.
Frescos, John, N.
Getman, Daniel, Pea.
Heinz, Robert, M.
Mishke, Brent, Buoy.
McDonald's, Joseph, Jay.
Abbas, Zaheel, Es.
Frescos, John, N.
Getman, Daniel, Pea.
Heinz, Robert, M.
Mishke, Brent, Buoy.
McDonald's, Joseph, Jay.
Application Number:
JP50719598A
Publication Date:
November 14, 2000
Filing Date:
July 22, 1997
Export Citation:
Assignee:
Monsanto Company
International Classes:
A61K31/18; A61K31/195; A61K31/215; A61K31/36; A61K31/40; A61K31/445; A61K31/47; A61K31/495; A61K31/505; A61K31/535; A61P27/00; C07C311/16; C07C311/17; C07C311/29; C07C323/25; C07C323/31; C07C323/32; C07C323/49; C07C323/58; C07C323/60; C07C323/67; C07C327/30; C07D207/48; C07D211/96; C07D213/42; C07D215/36; C07D231/20; C07D233/61; C07D233/64; C07D233/84; C07D239/46; C07D265/30; C07D277/28; C07D295/13; C07D307/54; C07D317/62; C07D333/20; C07D333/24; C07D333/34; C07D333/36; C07D333/38; C07D333/40; C07D333/62; C07D401/12; C07D409/04; C07D409/06; C07D409/12; C07D409/14; C07D413/04; C07D413/14; C07D295/12; C07D417/12; (IPC1-7): C07C323/25; A61K31/00; A61K31/18; A61K31/195; A61K31/215; A61K31/34; A61K31/36; A61K31/38; A61K31/40; A61K31/415; A61K31/425; A61K31/44; A61K31/445; A61K31/47; A61K31/495; A61K31/505; A61K31/535; C07C323/32; C07C323/58; C07C323/60; C07C323/67; C07C327/30; C07D207/48; C07D211/96; C07D213/42; C07D215/36; C07D231/20; C07D233/64; C07D233/84; C07D239/46; C07D277/28; C07D295/12; C07D307/54; C07D317/62; C07D333/20; C07D333/24; C07D333/34; C07D333/36; C07D333/38; C07D333/40; C07D333/62; C07D401/12; C07D409/04; C07D409/06; C07D409/12; C07D409/14; C07D413/04; C07D413/14; C07D417/12
Attorney, Agent or Firm:
Akira Asamura (3 outside)