Title:
【発明の名称】水溶性感圧粘膜接着剤
Document Type and Number:
Japanese Patent JPH09504810
Kind Code:
A
Abstract:
PCT No. PCT/US94/09305 Sec. 371 Date Aug. 3, 1995 Sec. 102(e) Date Aug. 3, 1995 PCT Filed Aug. 19, 1994 PCT Pub. No. WO95/05416 PCT Pub. Date Feb. 23, 1995Water-soluble pressure-sensitive adhesives include a water-soluble polymer that is made tacky at room temperature by addition of a water-soluble plasticizer that is miscible with the polymer. Suitable polymers are solid at room temperature; and have a hydrophilicity as measured by water uptake greater than about 25%; they are liquid at room temperature and have a boiling point higher than about 80 DEG C. The adhesives according to the invention may conveniently be provided in dry film form. Preferred water-soluble pressure-sensitive adhesives of the invention adhere both to mucosal surfaces and to a variety of materials that may constitute a part of a device or prosthesis to be held in a body cavity that has a mucosal lining. Also, a laminated device for the controlled release of a substance within a mucosa-lined body cavity includes the substance dissolved or dispersed in either or both of a water-soluble pressure-sensitive adhesive layer and optionally one or more water-soluble polymer layers. Also, devices for administering a substance over an extended time for relief of sore throat or cough, or for administering a breath freshening agent, particularly a mint odorant, include a water soluble polymer film layer containing the active ingredient, and a water soluble pressure sensitive mucoadhesive layer.
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Inventors:
Bigs Skis, James E.
Ben Katraman, Subsu.
Scott, Anne M.
Ben Katraman, Subsu.
Scott, Anne M.
Application Number:
JP50717195A
Publication Date:
May 13, 1997
Filing Date:
August 19, 1994
Export Citation:
Assignee:
Cygnus, Inc.
International Classes:
A61F6/06; A61F13/02; A61K6/00; A61K9/00; C08K5/10; C09J9/00; C09J101/08; C09J103/00; C09J103/02; C09J105/00; A61K9/70; C09J107/00; C09J129/04; C09J133/02; C09J137/00; C09J139/06; C09J171/00; C09J171/02; C09J189/00; C09J193/00; C09J201/00; A61F13/00; (IPC1-7): C09J201/00; A61K9/70; C09J9/00; C09J101/08; C09J103/00; C09J107/00; C09J129/04; C09J133/02; C09J139/06; C09J171/02; C09J189/00
Attorney, Agent or Firm:
Shusaku Yamamoto