Title:
【発明の名称】アミノ酸またはペプチドから誘導された両親媒性化合物,その合成方法およびその薬剤分配系としての応用
Document Type and Number:
Japanese Patent JPH07509709
Kind Code:
A
Abstract:
Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
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Inventors:
Guido, Camille
Pavia, Andre, A
Pucci, Bernard
Ries, Jean, Gee
The riff, Leila
Pavia, Andre, A
Pucci, Bernard
Ries, Jean, Gee
The riff, Leila
Application Number:
JP50502394A
Publication Date:
October 26, 1995
Filing Date:
August 05, 1993
Export Citation:
Assignee:
Alliance Pharmaceutical Corporation
International Classes:
A61K9/107; A61K9/00; A61K9/127; A61K47/26; C07C237/22; C07C323/60; C07H15/04; C07H15/06; C07K1/107; C07K1/113; C07K5/04; C07K7/04; (IPC1-7): C07C237/22; A61K9/107; A61K9/127; C07C323/60; C07K1/107; C07K5/04; C07K7/04
Attorney, Agent or Firm:
Tsutomu Toyama (3 others)