Title:
【発明の名称】第二アミン―酸化窒素付加物の抗高血圧組成物及びその用途
Document Type and Number:
Japanese Patent JPH05501402
Kind Code:
A
Abstract:
This invention concerns anti-hypertensive compositions and a method of lowering blood pressure in mammals. The active component of the compositions is a compound of the formula: I wherein R1 and R2 are independently chosen from straight chain and branched chain C1-C12 alkyl groups and benzyl, with the proviso that no branch occur on the alpha carbon atom of the alkyl groups; or R1 and R2 together with the nitrogen atom they are bonded to form a pyrrolidino, piperidino, piperazino or morpholino group, M+is a pharmaceutically acceptable cation, wherein X is the valence of the cation.
Inventors:
Kiefer, Larry, Kay
Rabbie, Joseph, Anthony
Dunhams, Tumbler, Marie
Wink, david, anderson
Rabbie, Joseph, Anthony
Dunhams, Tumbler, Marie
Wink, david, anderson
Application Number:
JP51401890A
Publication Date:
March 18, 1993
Filing Date:
September 07, 1990
Export Citation:
Assignee:
US HEALTH (US)
International Classes:
A61K9/08; A61K31/13; A61K31/135; A61K31/40; A61K31/445; A61K31/495; A61K31/535; A61K31/5375; A61P9/12; A61P35/00; C07C243/42; C07C291/08; C07C307/02; C07D295/22; C07D295/28; (IPC1-7): C07D295/22; A61K31/13; A61K9/08
Attorney, Agent or Firm:
Kazuo Sato (2 outside)