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Title:
【発明の名称】ジヒドロベンゾピランの組み合わせライブラリー
Document Type and Number:
Japanese Patent JP2001520638
Kind Code:
A
Abstract:
Combinatorial libraries are disclosed which are represented by Formula I: wherein: is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. These libraries contain dihydrobenzopyrans of the formula which interact (i.e., as agonists or antagonists) with alpha adrenergic receptors, dopamine receptors, sigma -opiate receptors, and K+ channels and are inhibitors of carbonic anhydrase isozymes. They are useful in the treatment of ocular diseases such as glaucoma.

Inventors:
John Jay Baldwin
Lawrence W. Dillard
Geely
John c. leader
Wengwang Zeng
Application Number:
JP51763697A
Publication Date:
October 30, 2001
Filing Date:
November 04, 1996
Export Citation:
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Assignee:
Pharmacopia, ink.
International Classes:
G01N33/50; A61K31/353; A61P9/12; A61P11/00; A61P11/06; A61P13/08; A61P25/18; A61P25/24; A61P25/28; A61P27/06; A61P43/00; C07B61/00; C07C201/12; C07C205/59; C07C233/01; C07C237/28; C07C237/42; C07D311/08; C07D311/22; C07D311/58; C07D311/68; C07D311/72; C07D311/96; C07D491/10; C07D491/107; C07D493/10; C07D493/20; C07D495/10; C07D495/20; C07D497/10; C07D497/20; C12Q1/00; C12Q1/527; G01N33/15; G01N33/543; G01N33/566; G01N33/573; (IPC1-7): C07D311/22; A61K31/353; A61P9/12; A61P11/00; A61P11/06; A61P13/08; A61P25/18; A61P25/24; A61P25/28; A61P27/06; A61P43/00; C07B61/00; C07C205/59; C07C237/28; C07C237/42; C07D311/58; C07D311/68; C07D311/72; C07D311/96; C07D491/107; C07D493/10; C07D495/20; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Ken Takahashi