Title:
【発明の名称】アレルギーまたは炎症疾患の治療用化合物
Document Type and Number:
Japanese Patent JP3192424
Kind Code:
B2
Abstract:
Novel cyclohexanes of formulas (I) and (II) are described herein. They inhibit the production of Tumor Necrosis Factor and are useful in the treatment of disease states mediated or exacerbated by TNF production; these compounds are also useful in the mediation or inhibition of enzymatic or catalytic activity of phosphodiesterase IV.
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Inventors:
Christensen, Siegfried Benjamin, The Force
Vendor, Paul Elliot
Forster, Cornelia Jutta
Vendor, Paul Elliot
Forster, Cornelia Jutta
Application Number:
JP51746793A
Publication Date:
July 30, 2001
Filing Date:
March 12, 1993
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORPORATION
International Classes:
A61K31/085; A61K31/12; A61K31/165; A61K31/275; A61P11/06; A61P29/00; A61P37/00; A61P37/08; A61P43/00; C07C43/315; C07C45/44; C07C45/51; C07C45/71; C07C47/47; C07C47/575; C07C49/753; A61K31/695; C07C49/757; C07C233/56; C07C235/80; C07C235/82; C07C255/37; C07C255/40; C07C255/46; C07C323/17; C07F7/08; C07F7/12; (IPC1-7): C07C43/315; C07C47/47; C07C49/753; C07C49/757; C07C235/80; C07C235/82; C07C255/37; C07C255/40; C07C323/17; C07F7/12
Domestic Patent References:
| JP5318546A |
Other References:
【文献】J.Org.Chem.,Vol.57,No.4(February 14,1992)p.1309-p.1313
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)