【発明の名称】レニン阻害剤、その製造方法、その使用のための方法およびそれを含有する組成物

Title:

【発明の名称】レニン阻害剤、その製造方法、その使用のための方法およびそれを含有する組成物

Document Type and Number:

Japanese Patent JPH03500880

Kind Code:

A

Abstract:

The invention concerns novel renin-inhibitory peptides which are useful for treating renin-associated hypertension, congestive heart failure, and hyperaldosteronism. Processes for preparing the peptides, novel intermediates useful in the preparation thereof, compositions containing them, and methods of using them are included. Also included is a diagnostic method which uses the compounds to determine the presence of renin-associated hypertension, congestive heart failure, or hyperaldosteronism.

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Inventors:

Hamilton, Harriet Wall
Hotuziez, Jiyoung Kuk
Lipine, Joseph Thomas
Circa, Islay

Application Number:

JP50938488A

Publication Date:

February 28, 1991

Filing Date:

October 25, 1988

Export Citation:

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Assignee:

Warner-Lambert Company

International Classes:

C07D295/22; A61K38/55; A61P5/38; A61P9/00; A61P9/12; C07C305/06; C07K5/02; C07K5/06; C07K14/81; (IPC1-7): A61K37/64; C07C305/06; C07D295/22; C07K5/06

Attorney, Agent or Firm:

Chika Takagi (2 outside)

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