Title:
【発明の名称】緑内障治療用組成物
Document Type and Number:
Japanese Patent JPS58500995
Kind Code:
A
Abstract:
A method for the treatment of glaucoma or lowering intraocular pressure in a mammal, involving topically administering to the eye of such mammal a selectively metabolized beta-blocking compound of the formula: wherein Ar may be substituted or unsubstituted aromatic, Y may be a straight or branched carbon chain or aralkyl, R may be lower alkyl, lower alkenyl, lower alkynyl, aryl, or aralkyl, and x is an integer from 1 to about 3; or a pharmaceutically acceptable salt thereof. Because of a relatively long duration of action of such compounds in ocular fluids and a relatively short duration of action in the systemic circulation, such compounds are useful for the treatment of excessive intraocular pressure without substantial systemic effects.
Inventors:
Mattia William Leslie-
Application Number:
JP50228182A
Publication Date:
June 23, 1983
Filing Date:
June 23, 1982
Export Citation:
Assignee:
American Hospital Supply Co-Poration
International Classes:
A61K31/215; A61K31/22; A61K31/24; A61K31/245; A61K31/275; A61K31/13; A61K31/60; (IPC1-7): A61K31/60; A61K31/245; A61K31/24; A61K31/215; A61K31/13
Attorney, Agent or Firm:
Hiroaki Tazawa