Title:
【発明の名称】葉酸-多糖複合体、その製造方法およびそれを活性成分として含む医薬組成物
Document Type and Number:
Japanese Patent JP2003533555
Kind Code:
A
Abstract:
The present invention relates to folic acid-polysaccharide complexs and method of preparation thereof, more particularly relates to folic acid-Dextran complexs, method of preparation thereof, pharmaceutical compositions having said complex as active component and uses of said composition in therapy of tumors. The folic acid-polysaccharide complexs of the present invention have general formula of: (X)n-Y, wherein X is identical or different, and is selected from folic acid, derivatives of folic acid and other substances that can enter into cell via the pathway of folic acid receptor; Y is polysaccharide; n ≥ 1.
Inventors:
Le, Way You
Liu, Min
Bread, Jun
Liu, Min
Bread, Jun
Application Number:
JP2001576896A
Publication Date:
November 11, 2003
Filing Date:
April 16, 2001
Export Citation:
Assignee:
Shanghai Farmco Research, Inc.
Fudan University
Fudan University
International Classes:
A61K9/19; A61K9/48; A61K31/715; A61K31/718; A61K31/721; A61K31/727; A61K31/787; A61P35/00; A61P35/04; C08B30/18; C08B37/00; C08B37/02; C08B37/10; (IPC1-7): C08B30/18; A61K9/19; A61K9/48; A61K31/715; A61K31/718; A61K31/721; A61K31/727; A61K31/787; A61P35/00; C08B37/00; C08B37/02; C08B37/10
Attorney, Agent or Firm:
Akira Asamura (3 outside)