Title:
【発明の名称】金属タンパク質加水分解酵素阻害剤であるヒドロキサム酸誘導体
Document Type and Number:
Japanese Patent JP2768554
Kind Code:
B2
Abstract:
Compounds of formula (V) : wherein R2 represents a group R6-A- wherein A represents a divalent straight or branched, saturated or unsaturated hydrocarbon chain of up to 6 C atoms which may be interrupted by an O or S atom, and R6 represents hydrogen or an optionally substituted phenyl, cycloalkyl or cycloalkenyl group; and the groups R12 and R13 are hydrogen, alkyl, phenyl or substituted phenyl; and activated derivatives thereof are useful as intermediates in the preparation of matrix metalloproteinase inhibitors..
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Inventors:
Dickins, Jonathan, Philip
Klimin, Michael, John
Beckett, Raymond, Paul
Klimin, Michael, John
Beckett, Raymond, Paul
Application Number:
JP50430794A
Publication Date:
June 25, 1998
Filing Date:
July 23, 1993
Export Citation:
Assignee:
British Biotech Pharmaceuticals Limited
International Classes:
A61K31/00; A61K31/16; A61K31/165; A61K31/19; A61K31/195; A61K31/38; A61K31/381; A61K31/395; A61K31/40; C07D295/14; A61K31/401; A61K31/4015; A61K31/415; A61K31/42; A61K31/421; A61K31/425; A61K31/426; A61K31/496; A61K31/505; A61K31/535; A61K31/5375; A61K31/5377; A61P1/02; A61P1/14; A61P7/02; A61P7/04; A61P9/00; A61P9/08; A61P9/10; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/00; A61P37/06; A61P43/00; C07C259/06; C07D207/27; C07D225/02; C07D231/12; C07D239/42; C07D263/32; C07D277/10; C07D277/20; C07D277/30; C07D317/30; C07D317/34; C07D333/24; C07D333/36; C07D521/00; C07D207/26; (IPC1-7): C07C259/06; A61K31/165; A61K31/19; A61K31/38; A61K31/40; A61K31/415; C07D207/27; C07D231/12; C07D333/24
Attorney, Agent or Firm:
Shintaro Nogawa