Title:
【発明の名称】erbB-2受容体タンパク質に結合し且つ細胞性応答を誘導するリガンド成長因子
Document Type and Number:
Japanese Patent JPH06505011
Kind Code:
A
Abstract:
The present invention relates to erbB-2 ligands and function derivatives thereof which are capable of binding to the erbB-2 transmembrane protein but fail to bind to epidermal growth factor receptor. The present invention further pertains to anti-ligand molecules capable of recognizing and binding to the erbB-2 ligand molecule and to screening assays for such ligands. The present invention additionally relates to uses for the erbB-2 ligand, the anti-ligand molecules and the screening assays.
Inventors:
Lippman, Mark Sea
Ruth, Ruth
Ruth, Ruth
Application Number:
JP50456792A
Publication Date:
June 09, 1994
Filing Date:
January 13, 1992
Export Citation:
Assignee:
GEORGETOWN UNIVERSITY
International Classes:
A61P35/00; C07K1/00; C07K14/005; C07K14/195; C07K14/475; C07K14/705; C07K16/00; A61K38/00; C07K16/22; C12N1/21; C12N15/09; C12N15/12; C12P21/02; G01N33/53; G01N33/566; G01N33/574; (IPC1-7): C07K15/04; A61K37/02; C12N15/12; C12P21/02; G01N33/53; G01N33/566; G01N33/574
Attorney, Agent or Firm:
Kyozo Yuasa (5 people outside)