【発明の名称】11β-長鎖置換型エストラトリエン、その製造方法、これらの11β-長鎖置換型エストラトリエンを含む医薬調製物、並びに医薬剤の製造のためのそれらの使用

Title:

Document Type and Number:

Japanese Patent JP2003503419

Kind Code:

A

Abstract:

This invention describes a 11beta-long-chain-substituted estratriene of general formula (I), in which R<11 >is a long-chain radical that has a nitrogen atom and optionally a sulfur atom, which in addition can be functionalized in the terminal position with a perfluoroalkyl group or an optionally substituted arly radical. The compound can have antiestrogenic or tissue-selective estrogenic properties and be suitable for the production of pharmaceutical agents.

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Inventors:

Ballman, Rolf
Heinrich, Nikolaus
Chlor, Jork
Sauer, Gerhard
Fritzheimer, Karl-Heinrich
Hegel-Hartunk, Krysta
Hoffman, Jens
Richterner, Rosemary
Zorn, Ludwig

Application Number:

JP2001507059A

Publication Date:

January 28, 2003

Filing Date:

June 26, 2000

Export Citation:

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Assignee:

Schering Actien Gezel Shaft

International Classes:

A61K31/565; A61K31/58; A61P5/30; A61P5/32; A61P17/14; A61P35/00; C07J1/00; C07J41/00; C07J43/00; (IPC1-7): C07J41/00; A61K31/565; A61K31/58; A61P5/32; A61P17/14; A61P35/00; C07J43/00

Domestic Patent References:

JPH06340688A	1994-12-13
JPH02268194A	1990-11-01
JPH10182466A	1998-07-07

Foreign References:

WO1999025725A1	1999-05-27
WO1998028324A1	1998-07-02

Attorney, Agent or Firm:

Takashi Ishida (4 others)

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