Title:
【発明の名称】ヒトr-インタ-フェロンの製造方法
Document Type and Number:
Japanese Patent JPS58502032
Kind Code:
A
Abstract:
Process for the production of human gamma-interferon by separating the leukocyte fraction (buffy coat) of blood, removing the erythrocytes, suspending the leukocytes in a suitable nutrient medium, treating the same with a mitogenic agent and separating the liquid containing interferon from the cells which comprises pre-treating the leukocytes with 200-20000 IU/ml. of alpha- or beta-interferon prior to treatment with the mitogenic agent. The advantage of the process is that the gamma-interferon production is increased by 500-1000 %.
Inventors:
Veraday Ilona
Toto Micros
Lost Tsui Istban
Toto Sandr
Endless Valeria
Toto Micros
Lost Tsui Istban
Toto Sandr
Endless Valeria
Application Number:
JP50000983A
Publication Date:
December 01, 1983
Filing Date:
November 30, 1982
Export Citation:
Assignee:
EDIT JOJI SERVE JET JET
International Classes:
C12P21/00; A61K35/14; A61K38/21; C07K14/00; C07K14/52; C07K14/555; C07K14/57; (IPC1-7): C12P21/00; A61K45/02; C07G7/00
Attorney, Agent or Firm:
Aoki Akira