Title:
【発明の名称】シス-2-ヒドロキシ-2-フエニル-r-1-シクロヘキサンカルボン酸の製造法
Document Type and Number:
Japanese Patent JPS6024781
Kind Code:
B2
Abstract:
A known effective choleretic, cis-2-hydroxy-2-phenyl-r-1-cyclohexane carboxylic acid is obtained with a novel method wherein 1-phenylcyclohexene is reacted with formaldehyde in formic acid or mixture of formic acid with other solvents. The reaction mixture is hydrolyzed (alkaline hydrolysis) to provide a substituted cyclohexanol concurrently with a substituted dioxan. The substituted diol is separated from the substituted dioxan and finally oxidized to obtain the expected acid.
Inventors:
KOSHIMO BURATSUCHI TORUSHI
Application Number:
JP13544876A
Publication Date:
June 14, 1985
Filing Date:
November 12, 1976
Export Citation:
Assignee:
GIDOTSUTEI INTERN SA HOORUDEINGU
International Classes:
C07C27/00; C07C29/38; C07C35/21; C07C51/00; C07C51/16; C07C62/32; C07C67/00; C07D319/08; (IPC1-7): C07C62/32; C07C51/16
Attorney, Agent or Firm:
Heiyoshi Odashima