Title:
【発明の名称】ジヒドロリゼルグ酸メチル及びメトキシルミリゼルグ酸メチルのN-メチル誘導体の製法
Document Type and Number:
Japanese Patent JPH0667937
Kind Code:
B2
Abstract:
A process for preparing an N-methyl derivative of methyl dihydrolysergate and methyl methoxylumilysergate, of formula: in which R1 denotes a hydrogen atom or a methoxy group, which comprises reacting a methylating agent with a compound of formula: in which R1 is defined as above, in the presence of a quaternary salt, in the presence of a solid metal alcoholate of formula CH3-OM in which M denotes an alkali metal atom, or an alkali metal hydride, and in the presence of a dehydrating agent of formula R2-COO-CH3 in which R2 denotes a hydrogen atom or an alkyl, alkyloxy, alkyloxycarbonyl or aryl group or of formula R3-C(OCH3)3 in which R3 denotes a hydrogen atom, an alkyl group or an aryl group.
Inventors:
Christian jeerbe
Application Number:
JP16097286A
Publication Date:
August 31, 1994
Filing Date:
July 10, 1986
Export Citation:
Assignee:
Loan-Pro-Santo
International Classes:
B01J31/00; B01J31/02; C07B61/00; C07D457/04; (IPC1-7): C07D457/04; B01J31/02; C07B61/00
Attorney, Agent or Firm:
Heiyoshi Odashima
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