Title:
【発明の名称】デルタ肝炎ウイルス感染症の治療法
Document Type and Number:
Japanese Patent JP2003528138
Kind Code:
A
Abstract:
A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
Inventors:
Casey, Jiyoung El
Colva, Brent E
Court, paul jey
Guerin, Jiyoung El
Tenant, Bad Sea
Chiyu, Chiyun Kay
Colva, Brent E
Court, paul jey
Guerin, Jiyoung El
Tenant, Bad Sea
Chiyu, Chiyun Kay
Application Number:
JP2001570255A
Publication Date:
September 24, 2003
Filing Date:
March 29, 2001
Export Citation:
Assignee:
GEORGETOWN UNIVERSITY
Cornell Research Foundation, Inc.
University of the Giosia Research Foundation Inc.
Cornell Research Foundation, Inc.
University of the Giosia Research Foundation Inc.
International Classes:
G01N33/50; A61K31/7072; A61K31/7088; A61K31/7105; A61K38/00; A61K38/21; A61K39/395; A61K45/00; A61K45/06; A61K48/00; A61P1/16; A61P31/14; A61P31/20; A61P43/00; C07H19/06; C07H19/10; C12N9/00; C12N15/09; C12N15/113; G01N33/15; G01N33/576; (IPC1-7): A61K31/7072; A61K31/7088; A61K31/7105; A61K38/00; A61K38/21; A61K39/395; A61K45/00; A61K48/00; A61P1/16; A61P31/20; A61P43/00; C07H19/06; C07H19/10; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Yoshio Kawaguchi (4 outside)