【発明の名称】エポチロン製造のための微生物形質転換法

Title:

【発明の名称】エポチロン製造のための微生物形質転換法

Document Type and Number:

Japanese Patent JP2002533114

Kind Code:

A

Abstract:

A microbial method for the preparation of an epothilone containing a terminal hydroxyalkyl group, comprising contacting at least one epothilone having a terminal alkyl group with an enzyme or microorganism capable of catalyzing the selective hydroxylation of said alkyl group to a hydroxyalkyl group, and effecting said hydroxylation.

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Inventors:

When In Li
James A. Mattson
Shaohua Juan
Kin Shin Lam
Grace A. McClure

Application Number:

JP2000591169A

Publication Date:

October 08, 2002

Filing Date:

December 21, 1999

Export Citation:

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Assignee:

BRISTOL-MYERS SQUIBB COMPANY

International Classes:

C07D493/04; C12N5/02; C12P17/08; C12P17/10; C12P17/18; C12P17/16; C12R1/01; (IPC1-7): C12P17/16

Attorney, Agent or Firm:

Aoyama Ryo (1 person outside)

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