Title:
【発明の名称】新規ルパン誘導体、その製造およびそれを含む医薬組成物
Document Type and Number:
Japanese Patent JPH08509968
Kind Code:
A
Abstract:
Lupane derivatives of general formula (I) in which R is a radical of general formula (II) for which R' is a hydrogen atom or an alkyl radical, X is carbamoyl, N-méthyl carbamoyl, aminocarbonyl or N-methylaminocarbonyl, Y is substituted phenylene of general formula (III), in which R1 and R2 are H, halogen, alkyl, alkyloxy or nitro, provided that both are not H, R DEG and R DEG DEG , which are the same or different, are hydrogen atoms or alkyl radicals and n is 6 to 12, m is 0 to 2 and p is 0 to 2, with: 6 < m+n+p < 12, the alkyl radicals (1 to 4C) being straight or branched. The invention also concerns the salts of said derivatives when they exist and their preparation. The products according to the invention are especially useful in the treatment of AIDS and in infections induced by the herpes family of viruses.
Inventors:
D'our, norbert
Ebels, Michel
Pujiyaddo, Christel
Françoise
Ebels, Michel
Pujiyaddo, Christel
Françoise
Application Number:
JP52505094A
Publication Date:
October 22, 1996
Filing Date:
May 06, 1994
Export Citation:
Assignee:
Loan-Poulin L'Oré Societe Anonym
International Classes:
A61K31/56; A61P37/04; C07C235/40; C07C235/50; C07C235/60; C07C237/22; C07C271/28; C07J3/00; (IPC1-7): C07J3/00; A61K31/56
Attorney, Agent or Firm:
Heiyoshi Odashima