Title:
【発明の名称】新規なベンゾピラン誘導体、その製造方法及びそれらを含有する製薬学的組成物
Document Type and Number:
Japanese Patent JP3061747
Kind Code:
B2
Abstract:
Arylalkyl piperazino alkyl benzopyran derivs. of formula (I), their optical isomers and acid and base addn. salts, are new. Ar = phenyl or naphthyl (both opt. substd. by 1-3 OH, alkyl (opt. substd. by one or more halo), alkoxy or halo); n = 1-4; when Rb = alkyl, then A = bond and Ra, Rc = H, halo, alkyl (opt. substd. by one or more halo) or alkoxy; when Rb+Rc = -(CH2)q-, then A = -(CH2)p- and Ra = OH or alkoxy in position 5, or H or halo ; or when Rb+Rc = -CH= single bonded to the aromatic ring, then A = CH2 and Ra = H, OH or alkoxy in position 5; or Rb+Rc = bond, then A = -C(=O)-CH= and Ra = H, hydroxy or alkoxy; p = 0- 2; q = 0- 2; provided that p + q = 1 or 2; when Rb = alkyl, then X, Y = H; or CXY = CO and Rd = H or alkyl; when Rb+Rc = (CH2)2 or -CH= then X, Y = H and Rd = H; all alkyl, alkoxy = 1-6C.
Inventors:
Genevieve Basual-Muiset
Salma Yune
Youssef Lovesitter
Marc Peyard
Daniel-Henri Cagnar
Pierre Renard
Mali-Claire Lutry
Salma Yune
Youssef Lovesitter
Marc Peyard
Daniel-Henri Cagnar
Pierre Renard
Mali-Claire Lutry
Application Number:
JP23243395A
Publication Date:
July 10, 2000
Filing Date:
September 11, 1995
Export Citation:
Assignee:
Adair e Company
International Classes:
A61K31/495; A61P19/02; A61P25/00; A61P25/20; A61P25/24; A61P25/26; A61P25/28; A61P29/00; A61P43/00; C07D295/092; C07D295/08; C07D295/18; C07D295/185; C07D307/81; C07D311/16; C07D311/20; C07D311/58; C07D311/66; (IPC1-7): C07D295/18; A61K31/495; A61P19/02; A61P25/28; A61P29/00; A61P43/00; C07D295/08; C07D307/81; C07D311/20; C07D311/58
Domestic Patent References:
| JP5253873A |
Attorney, Agent or Firm:
Hajime Tsukuni (2 outside)