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Title:
【発明の名称】新規なカルジオジラチン断片およびその製造方法
Document Type and Number:
Japanese Patent JP2819467
Kind Code:
B2
Abstract:
Described is a peptide fragment which comprises the amino acid sequence 95-126 of ANF/CDD 1-126 (gamma-hANaP) and is formed in the kidney. The fragment urodilatin (ANF/CDD 95-126) has the amino acid sequence (I), wherein R<1> and R<2> each represent further peptide fragments of ANF/CDD 1-126 (gamma-hANaP). In the amino acid sequence R<1> is Thr-Ala-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser and R<2> is Asn-Ser-Phe-Arg-Tyr. Further described are processes for the preparation and/or recovery of the new peptide fragment and a medicament containing urodilatin (ANF/CDD 95-126) as well as medical indications of the medicament.

Inventors:
Holzemann, Wolf-Georg
Alto, Janet M
Becker, Gerheld
Harpst, Franz
Application Number:
JP50200188A
Publication Date:
October 30, 1998
Filing Date:
February 27, 1988
Export Citation:
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Assignee:
Pharma Bissendorf Peptide Gamebehr
Wolf-Georg Holzemann
International Classes:
A61K38/00; A61K38/22; A61P1/16; A61P3/00; G01N33/53; A61P9/00; A61P9/12; A61P13/02; A61P15/00; A61P17/00; A61P25/00; A61P27/02; A61P39/02; C07K1/00; C07K1/04; C07K1/113; C07K1/14; C07K1/20; C07K1/36; C07K7/08; C07K14/575; C07K14/58; C07K16/00; A61K35/34; (IPC1-7): C07K14/58; A61K38/22; C07K1/36
Domestic Patent References:
JP61130236A
JP61501987A
Attorney, Agent or Firm:
Yasuo Yanagawa



 
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