Title:
【発明の名称】新規な1α―ヒドロキシビタミンD2エピマー、その誘導体及びそれらを含んでなる調剤
Document Type and Number:
Japanese Patent JPH0737443
Kind Code:
B2
Abstract:
The invention provides a new vitamin D2 compound, 1 alpha -hydroxy-24-epi-vitamin D2 and certain hydroxy-protected derivatives thereof. The new compound exhibits a distinctive activity pattern comprising high potency in stimulating intestinal calcium transport and little or no activity in inducing bone calcium mobilization or the differentiation of undifferentiated cells in culture, thereby evincing utility in the treatment of diseases characterized by loss of bone mass.
Inventors:
Deluca, Hector F.
Schnose, Heinrich K.
Pale Man, Kato El.
Schnose, Heinrich K.
Pale Man, Kato El.
Application Number:
JP50439790A
Publication Date:
April 26, 1995
Filing Date:
February 16, 1990
Export Citation:
Assignee:
Wisconsin Alumni Research Foundation
International Classes:
A61K31/592; A61P3/02; A61K31/59; A61P3/14; A61P19/10; A61P43/00; C07C401/00; (IPC1-7): C07C401/00; A61K31/59
Domestic Patent References:
| JP60501261Y |
Foreign References:
| US3907843A | 1975-09-23 |
Attorney, Agent or Firm:
Takao Kawasaki (1 outside)
Next Patent: トラクタにおける作業機連結装置