Title:
【発明の名称】因子Xaの新規インヒビター
Document Type and Number:
Japanese Patent JPH08504769
Kind Code:
A
Abstract:
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The novel compounds include peptide aldehyde analogues having substantial potency and specificity as inhibitors of mammalian factor Xa are further disclosed. The compounds are thought useful as inhibitors of factor xa in vitro or as a therapeutic agent for the prevention and treatment of conditions characterized by abnormal thrombosis in mammals. Intermediates useful for the preparation of the novel compounds are also disclosed.
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Inventors:
Blank, Terence Kevin
Webb, Thomas Roy
Lipka, William Charles
Webb, Thomas Roy
Lipka, William Charles
Application Number:
JP51452594A
Publication Date:
May 21, 1996
Filing Date:
December 15, 1993
Export Citation:
Assignee:
Corbus International, Inc.
International Classes:
A61P7/02; C07K5/02; A61K38/55; C07K5/062; C07K5/065; C07K5/087; A61K38/00; (IPC1-7): C07K5/065; A61K38/55; C07K5/062
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)