Title:
【発明の名称】アシルジアミンの製法
Document Type and Number:
Japanese Patent JPS5813535
Kind Code:
B2
Abstract:
Benzodiazocines corresponding to the formula are converted to benzodiazepines corresponding to the formula of claim 1 by subjecting the benzodiazocine (a) if it is halogen-substituted in the 3-position to a thermal treatment which may also take place in the presence of a nucleophilic agent for the reaction or (b) if the 3-position is hydroxy substituted to treatment with a Lewis acid which is a chlorinating or brominating agent. Whenever the diazepine obtained as the final product has a 2-halogenomethyl group it may then be converted to benzodiazepine which is otherwise substituted in the 2-position.
Inventors:
BORUFUGANGU MIRUKOFUSUKII
RENKE BUTSUDEN
JIIKUFURIITO FUNKE
RORUFU HYUTSUSHENSU
RENKE BUTSUDEN
JIIKUFURIITO FUNKE
RORUFU HYUTSUSHENSU
Application Number:
JP14866777A
Publication Date:
March 14, 1983
Filing Date:
December 09, 1977
Export Citation:
Assignee:
KALI CHEMIE AG
International Classes:
C07D317/66; A61K31/395; A61K31/55; A61K31/551; A61P25/00; A61P25/08; A61P25/20; A61P25/26; C07C67/00; C07C231/00; C07C231/02; C07C233/12; C07C233/78; C07C235/50; C07D243/14; C07D243/16; C07D243/28; C07D245/06; C07D319/18; C07D403/06; C07D405/02; C07D491/04; C07D491/056; C07C; C07D; (IPC1-7): C07C103/82; C07C102/00; C07D317/66
Attorney, Agent or Firm:
Toshio Yano