NOVEL ACETYLSALICYLIC ACID DERIVATIVE AND USE AS MEDICINE

Title:

NOVEL ACETYLSALICYLIC ACID DERIVATIVE AND USE AS MEDICINE

Document Type and Number:

Japanese Patent JPS58937

Kind Code:

A

Abstract:

2-(2-Methoxy -phenoxy)ethyl acetyl salicylate of formula (I) is new. Analgesic, antipyretic, antiinflammatory, and bronchosecretolytic agent, which is used to treat fevers, colds, rheumatic and neuralgia and esp. catarrhal and respiratory troubles associated with inflammation, fever, pain and tracheo-broncho-pulmonary troubles. (I) has lower toxicity than acetylsalicylic acid, superior analgesic, antipyretic and antiinflammatory activity than acetylsalicylic acid and a bronchosecretolytic activity comparable with that of gaiacol derivs. Activity and toxicity (LD50 of (I) oral in rats is 2934 mg/kg.; aspirin LD50 is 1400 mg/Kg).

Inventors:

REMO SUPANO
SERUJIO TEEDEESUCHI

Application Number:

JP10626782A

Publication Date:

January 06, 1983

Filing Date:

June 22, 1982

Export Citation:

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Assignee:

UNION SHIMIKA MEDEIKAMENTEIIDE

International Classes:

A61K31/60; A61P11/10; A61P25/04; A61P29/00; C07C69/90; (IPC1-7): A61K31/60; C07C69/90

Attorney, Agent or Firm:

Tsukimura Shigeru

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