Title:
【発明の名称】標的蛋白のリガンドを識別するためのスクリーニング方法
Document Type and Number:
Japanese Patent JP2952848
Kind Code:
B2
Abstract:
A novel method for screening chemical compounds (test ligands) for potential pharmaceutical effectiveness is provided. The disclosed method identifies possible therapeutic test ligands by placing them in the presence of target proteins and determining their ability to increase or decrease the ratio of folded target protein to unfolded target protein. The present methods do not require that biochemical function of the target protein be known, nor that any other ligands be previously identified.
Inventors:
ANDORYUU PAKUURA
JEEMUZU BOII
JEEMUZU BOII
Application Number:
JP23925296A
Publication Date:
September 27, 1999
Filing Date:
September 10, 1996
Export Citation:
Assignee:
SUKURIPUTOJEN PHARM INC
International Classes:
A61K38/16; A61K38/43; A61K45/00; C12Q1/37; G01N33/15; G01N33/566; G01N33/569; G01N33/573; G01N33/53; G01N33/68; G01N33/72; (IPC1-7): G01N33/15; A61K45/00; G01N33/566; G01N33/68; G01N33/72
Domestic Patent References:
| JP6294798A | ||||
| JP6503948A |
Attorney, Agent or Firm:
Sakai Hajime