Title:
PHOSPHOLIPID
Document Type and Number:
Japanese Patent JPS59163389
Kind Code:
A
Abstract:
NEW MATERIAL:A compound shown by the formula I (R1 and R2 are 9W10C aliphatic hydrocarbon; R3, R4, and R5 are H, lower alkyl, or linked to N atom to form cyclic ammonia group).
EXAMPLE: 2,3-Didecyloxypropyl 2-trimethylammonioethyl phosphate.
USE: An antitumor agent.
PREPARATION: For example, a compound (e.g., 2,3-didecylglycerol, etc.) shown by the formula II is reacted with a compound (e.g., 2-bromoethyldichloridate, etc.) shown by the formula III to give a compound shown by the formula IV, which is hydrolyzed and reacted with a tertiary amino compound (e.g., trimethylamine, etc.) shown by the formula V to give a compound shown by the formula I .
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Inventors:
NOJIMA SHIYOUSHICHI
NOMURA MASAAKI
NOMURA MASAAKI
Application Number:
JP3718783A
Publication Date:
September 14, 1984
Filing Date:
March 07, 1983
Export Citation:
Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
NOJIMA SHIYOUSHICHI
NOJIMA SHIYOUSHICHI
International Classes:
C07F9/10; A61K9/127; (IPC1-7): A61K9/56; C07F9/10
Attorney, Agent or Firm:
Hiroshi Iwata