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Patent Searching and Data


Title:
PREPARATION OF 1-(O-CHLOROTRITYL)-IMIDAZOLE
Document Type and Number:
Japanese Patent JPS5995275
Kind Code:
A
Abstract:

PURPOSE: To obtain the titled compound economically without using an unstable substance and an inexpensive reagent, by reacting o-chlorophenyl bisphenyl methanol as a raw material with acetyl chloride and acetylimidazole successively.

CONSTITUTION: o-Chlorophenyl bisphenol methanol as a raw material is reacted with acetyl chloride, and with acetylimidazole or cyanoimidazole in the presence of an alkali(e.g., hydroxide, carbonate, bicarbonate of alkali metal), to give the desired compound. An inert solvent such as acetonitrile, dichloromethane, acetone, etc. is used as a solvent. Acetyl imidazole as the raw material, for example, is obtained by reacting imidazole with acetic anhydride. Cyanoimidazole is obtained by reacting acetyl imidazole with cyanogen bromide.


Inventors:
TOMIYAMA TAKESHI
Application Number:
JP20343382A
Publication Date:
June 01, 1984
Filing Date:
November 19, 1982
Export Citation:
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Assignee:
KOTOBUKI SEIYAKU CO LTD
International Classes:
C07D233/62; (IPC1-7): C07D233/62
Attorney, Agent or Firm:
Hideo Nagata