PREPARATION OF L-ISOLEUCINE COMPOUND - DAIICHI KAGAKU YAKUHIN KK

Title:

PREPARATION OF L-ISOLEUCINE COMPOUND

Document Type and Number:

Japanese Patent JPS5934890

Kind Code:

A

Abstract:

PURPOSE: To prepare L-isoleucine compound in high efficiency, by the microbial action using dl-α-keto-β-methylvaleric acid as a raw material.

CONSTITUTION: A microbial strain belonging to Bacillus genus or Micrococcus genus, etc. and capable of converting dl-α-keto-β-methylvaleric acid to an L- isoleucine compound, e.g. Bacillus subtilis IFO-3073, is cultured, and the cultured product, cultured cell, or treated cell is made to react with dl-α-keto-β- methylvaleric acid or its salt in an aqueous buffer solution containing ammonium salt of inorganic acid or organic acid or urea, at 5.0W11pH and 15W60°C, and the produced L-isoleucine compound is separated from the product.

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Inventors:

AKIMOTO TOSHIYUKI
WATANABE MITSUO
ITOU NOBORU
ASANO KAZUO

Application Number:

JP14324382A

Publication Date:

February 25, 1984

Filing Date:

August 20, 1982

Export Citation:

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Assignee:

DAIICHI KAGAKU YAKUHIN KK

International Classes:

C12P13/06; C12R1/01; (IPC1-7): C12P13/06

Attorney, Agent or Firm:

Kazuyuki Satomi

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