Title:
UNSATURATED FATTY ACID DERIVATIVE
Document Type and Number:
Japanese Patent JPS6048971
Kind Code:
A
Abstract:
NEW MATERIAL:An unsaturated fatty acid 3-aminomethylpyridinamide.
EXAMPLE: 5,8,11,14,17-Dicosapentaenoic acid 3-aminomethylpyridinamide.
USE: Having preventing effect on thrombosis and cancerous metastasis, useful as a preventing for thrombosis participating in blood platelet aggregation, such as myocardial infarction, cerebral thrombosis, etc., and useful as a preventive for cancerous metastasis. Oral administration is preferable.
PREPARATION: An unsaturated fatty acid is reacted with 3-aminomethylpyridine in the presence of a condensation agent, to give the titled compound. N,N- Dicyclohexylcarbodiimide, 2-chloro-1-methylpyridinium p-toluenesulfoante, etc. may be cited as the condensation agent.
Inventors:
KUMONAKA YASUHIRO
TAKAHASHI KEIKO
WAKABAYASHI TOSHIO
TAKAHASHI KEIKO
WAKABAYASHI TOSHIO
Application Number:
JP15539583A
Publication Date:
March 16, 1985
Filing Date:
August 25, 1983
Export Citation:
Assignee:
TERUMO CORP
International Classes:
C07D213/38; A61K31/44; A61K31/4418; A61P7/02; C07D213/40; (IPC1-7): A61K31/44; C07D213/40