Title:
MANUFACTURE OF 1,3-DIHYDRO-4-PYRIDOYL-2H-IMIDAZOL-2-ONE
Document Type and Number:
Japanese Patent JPS6143167
Kind Code:
A
Abstract:
1,3-Dihydro-4-pyridoyl-2H-imidazol-2-ones are prepared in a three step process by a) reducing 1-pyridyl-1,3-deketo-2-oximinoalkanes to produce 1-pyridyl-1-hydroxy-2-amine-3-ketoalkanes; b) reacting the thus produced hydroxyaminoketone with cyanate ion to produce a 1,3-dihydro-4-hydroxy(pyridyl)methyl-2H-imidazol-2-one; and c) oxidizing the thus produced hydroxymethyl compound to yield the desired product.
Inventors:
RICHIYAADO EE SHIYUNETSUTORAA
CHIIHISUN AARU KINGU
CHIIHISUN AARU KINGU
Application Number:
JP16605885A
Publication Date:
March 01, 1986
Filing Date:
July 29, 1985
Export Citation:
Assignee:
MERRELL DOW PHARMA
International Classes:
A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/4427; A61P9/04; B01J23/34; B01J23/44; C07D213/46; C07D213/48; C07D213/50; C07D401/06; (IPC1-7): A61K31/44; C07D213/00; C07D213/50; C07D233/00; C07D401/06
Attorney, Agent or Firm:
Yataro Sasai (1 person outside)