Title:
(+)- AND (-)-6-METHOXY-ALPHA-METHYL-2-NAPHTHALENEACETIC ACID:N-METHYL-D-GLUCAMINE SALT MIXTURE
Document Type and Number:
Japanese Patent JPS59193845
Kind Code:
A
Abstract:
The subject of the invention is a process for resolving mixtures of (+)- and (-)-6-methoxy- alpha -methyl-2-naphthaleneacetic acid into the enantiomers thereof, characterized in that N-methyl-D-glucamine [=1-deoxy-1-(methylamino)-D-glucitol] is used as the resolving agent, so that the 6-methoxy- alpha -methyl-2-naphthaleneacetic acid is converted into the corresponding diastereoisomeric N-methyl-D-glucamine salt pair which, because of very different solubilities, can be separated easily and completely with high yield.
Inventors:
ERUNSUTO FUERUDAA
DABUIDE PITORE
HANSU TSUTSUTAA
DABUIDE PITORE
HANSU TSUTSUTAA
Application Number:
JP15260483A
Publication Date:
November 02, 1984
Filing Date:
August 23, 1983
Export Citation:
Assignee:
SYNTEX INC
International Classes:
C07B31/00; C07B57/00; C07C51/00; C07C59/64; C07C51/487; C07C51/64; C07C67/00; C07C53/136; (IPC1-7): C07B19/00; C07C51/487; C07C59/64
Attorney, Agent or Firm:
Heikichi Odashima