Title:
【発明の名称】精製されたマルチメラーゼ
Document Type and Number:
Japanese Patent JP2000508918
Kind Code:
A
Abstract:
There is disclosed a purified multimerase having an indirect and a direct proteolytic activity, which converts vWF having a singlet structure to vWF having a satellite structure and is active in the presence of the serine protease inhibitor DFP or the calpain protease inhibitor Z-Leu-Leu-Tyr-CHN2, as well as a method of preparing the multimerase according to the invention.
Inventors:
Furlan, Miha
Remle, Bernhard
Schwarz, Hans-Peter
Tretzek, Peter
Ible, Johann
Remle, Bernhard
Schwarz, Hans-Peter
Tretzek, Peter
Ible, Johann
Application Number:
JP53857297A
Publication Date:
July 18, 2000
Filing Date:
April 25, 1997
Export Citation:
Assignee:
IMMUNO AKTIENGESELLSCHAFT
International Classes:
A61K31/00; A61K38/46; A61P7/00; A61P7/02; A61P7/04; C07K14/755; C07K16/18; C12N9/64; C12Q1/37; A61K38/00; (IPC1-7): C12N9/64; C07K16/18; C12Q1/37
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)