TNF-α PRODUCTION INHIBITOR, ESTROGENIC AGENT AND EXTERNAL PREPARATION FOR SKIN

Japanese Patent JP2005213178

A

To provide a new TNF-α production inhibitor which contains a TNF-α production inhibitory substance as an active ingredient, a new estrogenic agent containing an estrogenic substance as an active ingredient and an external preparation for the skin wherein the TNF-α production inhibitor or the estrogenic agent is compounded.

The TNF-α production inhibitor or the estrogenic agent contains nobiletin, at least one citrus extract chosen from the group consisting of extracts from Citrus hassaku Hort., Citrus unshiu Marcov., grapefruit, Valencia orange, Citrus depressa Hayata, Citrus reticulata Blanco, lemon, marcott and Shiranui or a nobiletin purified product obtained by purifying the citrus extract as an active ingredient. The external preparation for the skin contains the TNF-α production inhibitor or the estrogenic agent.

KISO AKINORI
ITO YOKO
OTO NOBUAKI
KISHIDA NAOKO

JP2004020823A

August 11, 2005

January 29, 2004

Click for automatic bibliography generation  

MARUZEN PHARMA

C07D311/30; A61K8/00; A61K8/49; A61K8/96; A61K8/97; A61K31/352; A61K36/75; A61P17/00; A61P17/06; A61P17/16; A61P29/00; A61P37/06; A61P43/00; A61Q19/00; (IPC1-7): A61K31/352; A61K7/00; A61K7/48; A61K35/78; A61P17/00; A61P17/06; A61P17/16; A61P29/00; A61P37/06; A61P43/00; C07D311/30

JPS62273915A	1987-11-28
JP2002053480A	2002-02-19
JP2001151679A	2001-06-05
JP2000080035A	2000-03-21
JP2003277274A	2003-10-02
JP2002226323A	2002-08-14
JP2003113068A	2003-04-18
JP2003128562A	2003-05-08
JP2003128569A	2003-05-08
JP2002000333A	2002-01-08
JP2003192588A	2003-07-09
JP2002003363A	2002-01-09

US6184246B1

2001-02-06

Yuji Hayakawa
Suzuki Keiyasu

Previous Patent: STABLE SUPPOSITORY COMPOSITION, SUPPOSITORY AND THEIR MANUFACTURING METHODS

Next Patent: CATALYST LAYER AND METHOD FOR FORMING THE SAME, FIXED BED TUBULAR REACTOR, METHOD FOR PRODUCING METH...