Title:
免疫関連障害に対する局部治療に使用するための局所LFA-1アンタゴニスト
Document Type and Number:
Japanese Patent JP2011521896
Kind Code:
A
Abstract:
This invention provides specifically formulated LFA-I antagonists or pharmaceutically acceptable salts thereof that are suitable for topical delivery. In particular, the LFA-I antagonists are particularly well suited for localized treatment by having a rapid systemic clearance rate. The invention also encompasses methods of treatment and prevention of immune related disorders using the LFA-I topical formulations of the present invention.
Inventors:
Vernier, john
Gadek, Thomas
Gadek, Thomas
Application Number:
JP2011505028A
Publication Date:
July 28, 2011
Filing Date:
April 15, 2009
Export Citation:
Assignee:
Sir code corporation
International Classes:
A61K45/00; A61K31/198; A61K31/381; A61K31/4709; A61K31/472; A61K31/4725; A61K31/496; A61K31/502; A61K31/517; A61P1/02; A61P1/18; A61P11/00; A61P11/06; A61P17/04; A61P17/06; A61P17/08; A61P17/14; A61P19/02; A61P27/02; A61P27/04; A61P27/14; A61P29/00; A61P37/02; A61P37/06; A61P43/00; C07D333/40; C07D217/26; C07D401/06; C07D401/12; C07D405/06; C07D405/14; C07D409/12; C07D409/14; C07D471/04
Domestic Patent References:
| JP2011516607A | 2011-05-26 | |||
| JP2011518155A | 2011-06-23 |
Foreign References:
| WO2006125119A1 | 2006-11-23 | |||
| WO2005044817A1 | 2005-05-19 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita