To provide a nonsurgical treatment for treating anal fissure and/or hemorrhoid or other benign anal diseases.

The single nifedipine which is a calcium channel inhibitor, or a selective combination thereof with bethanechol is topically applied to the anus to treat the benign anal diseases, especially the anal fissure and/or the hemorrhoid. The medicament induces the reduction of a mean pressure and a resting pressure, and thereby assists the recover of the anal fissure or the hemorrhoid. The amount of the nifedipine or a pharmaceutically acceptable salt thereof in the proportion of 0.5-10 wt.% is preferably present in a preparation.