Title:
経皮吸収製剤
Document Type and Number:
Japanese Patent JP4825305
Kind Code:
B2
Abstract:
[PROBLEMS] To improve the stability of a natural type sex hormone and the permeation in a transdermally absorbable preparation containing the natural type sex hormone to thereby increase the systemic effect and the long-acting property of the preparation. [MEANS FOR SOLVING PROBLEMS] The preparation comprises a natural type sex hormone, a polyoxyethylene oleyl ether having a molar number of ethylene oxide units added of 20, at least two kinds of oily ingredients selected from the group consisting of diisopropyl adipate, cetyl alcohol, benzyl alcohol, and propylene glycol dicaprate, a polyhydric alcohol, and ethanol.
Inventors:
Ryoki Matsui
Osamu Ueda
Osamu Ueda
Application Number:
JP2009533035A
Publication Date:
November 30, 2011
Filing Date:
September 10, 2008
Export Citation:
Assignee:
Shiseido Co., Ltd.
International Classes:
A61K31/565; A61K9/06; A61K31/566; A61K31/568; A61K31/5685; A61K31/57; A61K47/10; A61K47/14; A61K47/34; A61P5/26; A61P5/30; A61P15/10; A61P15/12; A61P19/10
Domestic Patent References:
| JP2000344671A | 2000-12-12 | |||
| JPH11279064A | 1999-10-12 | |||
| JPH0525038A | 1993-02-02 | |||
| JP2001505930A | 2001-05-08 | |||
| JPH09176049A | 1997-07-08 | |||
| JPH1072351A | 1998-03-17 | |||
| JP2007210941A | 2007-08-23 | |||
| JPH04103528A | 1992-04-06 | |||
| JPH1072353A | 1998-03-17 | |||
| JPH04346922A | 1992-12-02 | |||
| JPS6016917A | 1985-01-28 |
Foreign References:
| WO1996015776A1 | 1996-05-30 |
Attorney, Agent or Firm:
Yanagita Seiji
Go Sakuma
Kaori Kono
Go Sakuma
Kaori Kono