Title:
転移水素化方法及び触媒
Document Type and Number:
Japanese Patent JP4090078
Kind Code:
B2
Abstract:
A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centers. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.
Inventors:
Blacker, Andrew John
Mellow, ben james
Mellow, ben james
Application Number:
JP54445198A
Publication Date:
May 28, 2008
Filing Date:
March 20, 1998
Export Citation:
Assignee:
NP Pharmaceuticals (YK) Limited
International Classes:
C07C29/136; B01J31/18; B01J31/22; C07B31/00; C07B61/00; C07C29/143; C07C33/22; C07C35/23; C07C209/52; C07C211/03; C07F15/00
Domestic Patent References:
| JP55127323A | ||||
| JP11507917A | ||||
| JP9157196A |
Other References:
Chem. Ber., 1993, Vol.126, p.2421-2427
J. Chem. Soc. Dalton Trans., 1978, p.617-626
J. Am. Chem. Soc., 1995, Vol.117, p.7562-7563
J. Chem. Soc. Dalton Trans., 1978, p.617-626
J. Am. Chem. Soc., 1995, Vol.117, p.7562-7563
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Hiroaki Noya