Title:
無細胞タンパク質合成系に用いるための翻訳促進剤及びその利用
Document Type and Number:
Japanese Patent JP6440820
Kind Code:
B2
Abstract:
This specification provides a translation enhancer that makes it possible to obtain translation template mRNA efficiently in a cell-free protein synthesis system and, in turn, to realize excellent translation efficiency. Therefore, in this specification, a nucleic acid of at most 200 bases in length as a 3' untranslated region linked adjacent to the 3' end of a coding region that encodes the amino acid sequence of a desired protein, is used as a translation enhancer in a cell-free protein synthesis system.
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Inventors:
Yasuomi Tada
Mika Nomoto
Mika Nomoto
Application Number:
JP2017505359A
Publication Date:
December 19, 2018
Filing Date:
March 08, 2016
Export Citation:
Assignee:
Nagoya University
International Classes:
C12N15/11; C12P21/02
Domestic Patent References:
| JP2005247857A | ||||
| JP2002095483A | ||||
| JP8509381A |
Foreign References:
| WO2003106675A1 |
Other References:
Bioorg. Med. Chem. Lett., 2014, Vol. 24, pp. 3724-3727
Biotechnol. J., 2014, Vol. 9, pp. 641-651
PNAS, 2002, Vol. 99, No. 23, pp. 14652-14657
Biotechnol. J., 2014, Vol. 9, pp. 641-651
PNAS, 2002, Vol. 99, No. 23, pp. 14652-14657
Attorney, Agent or Firm:
Seiji Matsumoto