Title:
移植用チャンバーおよび移植用デバイス
Document Type and Number:
Japanese Patent JP6790267
Kind Code:
B2
Abstract:
According to the present invention, there are provided a chamber for transplantation, including a membrane for immunoisolation including a porous membrane at at least part of a boundary between an inside and an outside of the chamber for transplantation, in which the porous membrane contains a polymer and has a layered compact portion where a pore diameter is the smallest within the membrane, a pore diameter continuously increases in a thickness direction from the compact portion toward both one surface A and the other surface B of the porous membrane, a porosity in a vicinity of the surface B is 65% or more, an average pore diameter of the surface B is larger than an average pore diameter of the surface A, the surface B is disposed on the inside of the chamber for transplantation, and a joint portion at which the porous membranes are joined to each other while the surface B's face each other is provided; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein. In the chamber for transplantation of the present invention, a deterioration in substance permeability is unlikely to occur and a strength of the joint portion between the membranes for immunoisolation is high.
Inventors:
Kazuhiro Hasegawa
Ryuta Takegami
Shincho Kuniyuki
Mochizuki Yusuke
Ryuta Takegami
Shincho Kuniyuki
Mochizuki Yusuke
Application Number:
JP2019527033A
Publication Date:
November 25, 2020
Filing Date:
June 28, 2018
Export Citation:
Assignee:
FUJIFILM Corporation
International Classes:
A61L27/18; A61F2/02; A61K38/28; A61L27/14; A61L27/26; A61L27/54; A61L27/56; A61M1/14; A61P3/10
Domestic Patent References:
| JP2005349093A |
Foreign References:
| WO2016117565A1 | ||||
| WO2018088452A1 |
Other References:
PETERSEN, P. et al.,Improved Diffusion Properties of a New Polysulfone Membrane for the Development of a Bioartificial P,Transplantation Proceedings,2001年,Vol. 33,p.1952-1953
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes