Title:
微生物の増殖及びバイオフィルム形成に抵抗性のある移植し得る又は挿入可能な医療装置
Document Type and Number:
Japanese Patent JP2007525287
Kind Code:
A
Abstract:
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
Inventors:
Kato Freen M Miller
Weenna Bukai-Kout
Jian Min Li
Weenna Bukai-Kout
Jian Min Li
Application Number:
JP2007500937A
Publication Date:
September 06, 2007
Filing Date:
February 24, 2005
Export Citation:
Assignee:
Boston Scientific Saimed, Inc.
International Classes:
A61L27/00; A61F2/84; A61L31/00; A61L2/232; A61L29/16; A61L29/18; A61L31/04; A61L31/16; A61L31/18; A61M25/00
Foreign References:
| WO2003066119A1 | 2003-08-14 | |||
| US20030018306A1 | 2003-01-23 |
Attorney, Agent or Firm:
Toru Ishikawa