Title:
上昇したアルギナーゼ状態を含む、低下した一酸化窒素バイオアベイラビリティに関連する状態の治療
Document Type and Number:
Japanese Patent JP4723476
Kind Code:
B2
Abstract:
The invention features methods and compositions for treatment of conditions associated with decreased nitric oxide bioavailability, such as a condition associated with elevated arginase activity, using an arginine-based therapy, including combination therapy with an arginase inhibitor and/or magnesium
Inventors:
Morris Claudia Earl.
Application Number:
JP2006503579A
Publication Date:
July 13, 2011
Filing Date:
February 13, 2004
Export Citation:
Assignee:
Children's Hospital and Research Center at Auckland
International Classes:
A61K31/198; A61K31/195; A61K31/28; A61K31/69; A61K33/00; A61K33/06; A61K45/00; A61K45/06; A61P7/06; A61P9/12; A61P11/06; A61P43/00; A61K
Domestic Patent References:
| JP2002516856A | ||||
| JP8333313A | ||||
| JP10087497A | ||||
| JP10087498A | ||||
| JP2002047183A |
Foreign References:
| WO2002024002A1 |
Other References:
Br. J. Pharmacol.,2000年,130,1793-1798
Cell. Mol. Life. Sci.,1999年,55,1015-1028
Br. J. Pharmacol.,1997年,121,395-400
Biochemistry,2001年,40,9356-9362
Cell. Mol. Life. Sci.,1999年,55,1015-1028
Br. J. Pharmacol.,1997年,121,395-400
Biochemistry,2001年,40,9356-9362
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Kazuya Kawamoto
Toshi Gobe
Koichi Niimi
Kazuya Kawamoto