Title:
冠動脈疾患の治療
Document Type and Number:
Japanese Patent JP2006514929
Kind Code:
A
Abstract:
The invention provides a method of treating coronary artery disease in a human patient comprising directly injecting into an ischemic cardiac muscle, via multiple injections to different points of the cardiac muscle, a dose of a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding an angiogenic peptide operably linked to a promoter, whereby the coronary artery disease is treated.
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Inventors:
Pressler, Milton, Elle.
Black, Donald, M.
Fitcher, Paul, H.
Rasmussen, Henrik, S.
Samin, Margaret
Yonehiro, Grant
Black, Donald, M.
Fitcher, Paul, H.
Rasmussen, Henrik, S.
Samin, Margaret
Yonehiro, Grant
Application Number:
JP2004553607A
Publication Date:
May 18, 2006
Filing Date:
November 14, 2003
Export Citation:
Assignee:
Jembek, Incorporated
Warner-Lambert Company
Warner-Lambert Company
International Classes:
A61K48/00; A01N63/00; A61K31/7088; A61K35/76; A61M31/00; A61P9/10; C12N15/63; C12N15/861; C12N15/09
Attorney, Agent or Firm:
Takashima Ichi