Title:
EGR-1エンハンサー要素に関連する疾患の処置
Document Type and Number:
Japanese Patent JP2007509035
Kind Code:
A
Abstract:
Compounds and methods are provided for treating patients suffering from health condition associated with an expression state of a gene such as fertility disorders, cancer, proliferative diseases, vascular diseases, wounds requiring therapeutic intervention, inflammation, and pulmonary disorders by administering to said patient a compound capable of modulating egr-1 and/or an egr-1 response element consensus sequence thereby altering the expression state of said gene. Also described are new methods for screening compounds to identify effectors of egr-1 and/or egr-1 consensus sequence elements and methods for treating patients by administering such effectors to modulate egr-1 and/or egr-1 consensus sequences to thereby modify expression of genes associated therewith to in turn treat diseases or other physiological conditions associated with such gene expression.
Inventors:
One, norman
Tucker, Joe
McCafely, David Robert
Tucker, Joe
McCafely, David Robert
Application Number:
JP2006529525A
Publication Date:
April 12, 2007
Filing Date:
October 08, 2004
Export Citation:
Assignee:
Resverlogics Corporation
International Classes:
A61K45/00; A61K31/015; A61K31/04; A61K31/05; A61K31/085; A61K31/122; A61K31/352; A61K31/353; A61K31/397; A61K31/40; A61K31/404; A61K31/44; A61K31/505; A61K31/66; A61K35/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P15/08; A61P17/02; A61P29/00; A61P35/00; A61P39/06; C07C15/18; C07C39/15; C07C203/10; C07C311/21; C07C317/22; C07C323/18; C07D205/08; C07D207/416; C07D209/12; C07D213/48; C07D239/42; C07D309/30; C07D311/30; C07D311/32; C07D311/36; C07D311/38; C07D407/14; C12Q1/02; C12Q1/68; C07D207/40; C12N15/09
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita