Title:
TREATMENT OF DYSKINESIA
Document Type and Number:
Japanese Patent JP2011037877
Kind Code:
A
Abstract:
To provide the use of compounds which selectively inhibit μ opioid receptor activity or activation for the treatment of dyskinesia (which, for example, may arise as a side effect of L-DOPA therapy).
The compounds being desirably used are μ opioid receptor antagonists such as cyprodime. These are desirably used in the case wherein dyskinesia is expressed as chorea or dystonia or in the case where the patient has been subjected to dopamine replacement therapy with L-DOPA.
Inventors:
BROTCHIE JONATHAN
Application Number:
JP2010228049A
Publication Date:
February 24, 2011
Filing Date:
October 08, 2010
Export Citation:
Assignee:
MOTAC NEUROSCIENCE LTD
International Classes:
A61K45/00; A61K31/00; A61K31/415; A61K31/4184; A61K31/485; A61K48/00; A61P25/00; A61P25/02; A61P25/14; A61P25/16; A61P25/18; A61P25/30; A61P43/00
Domestic Patent References:
| JPH06505747A | 1994-06-30 |
Foreign References:
| WO1997007212A1 | 1997-02-27 |
Other References:
JPN5001016061; ＨＥＮＲＹ Ｂ ＡＮＤ ＢＲＯＴＣＨＩＥ ＪＮ: ＤＲＵＧＳ ＡＮＤ ＡＧＩＮＧ Ｖｏｌ．９ Ｎｏ．３, 1996, ｐｐ．１４９-１５８
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Samejima Mutsumi
Masahiro Nitta
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